Characterisation of Physical Frailty and Associated Physical and Functional Impairments in Mild Cognitive Impairment

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Characterisation of Physical Frailty and Associated Physical and Functional Impairments in Mild Cognitive Impairment

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Identification of mild cognitive impairment disease using brain functional connectivity and graph analysis in fMRI data

Background: Early diagnosis of patients in the early stages of Alzheimer's, known as mild cognitive impairment, is of great importance in the treatment of this disease. If a patient can be diagnosed at this stage, it is possible to treat or delay Alzheimer's disease. Resting-state functional magnetic resonance imaging (fMRI) is very common in the process of diagnosing Alzheimer's disease. In th...

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Correlates of frailty in Alzheimer's disease and mild cognitive impairment.

SIR—The global prevalence of dementia is rising with Alzheimer’s disease (AD) accounting for 50–60% of all cases and mild cognitive impairment (MCI) its precursor [1, 2]. Although the clinical hallmark of AD is progressive loss of memory and cognition, several studies have also shown changes in mobility and body composition suggesting frailty [3, 4]. Frailty represents age-related reduction in ...

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ژورنال

عنوان ژورنال: Frontiers in Medicine

سال: 2017

ISSN: 2296-858X

DOI: 10.3389/fmed.2017.00230